Glossary

    MC4 Receptor

    A melanocortin receptor in the CNS involved in sexual arousal and appetite regulation.

    Definition

    The MC4 receptor is one of the central melanocortin receptors involved in sexual arousal and appetite regulation. On TruthTides, MC4 is referenced as a primary target of PT-141 (Bremelanotide), an FDA-approved melanocortin receptor agonist that acts on MC3 and MC4 receptors in the central nervous system to modulate sexual desire. This central mechanism distinguishes PT-141 from PDE5 inhibitors such as sildenafil, which act peripherally on blood flow rather than centrally on desire.

    Source: PT-141 peptide summary and FAQ